Orglu Tablets contain phloroglucinol, an organic compound belonging to the class of musculotropic antispasmodics, with the molecular formula C6H6O3. It works by targeting smooth muscles in the gastrointestinal and urogenital tracts, helping to reduce pain caused by spasms. The formulation also includes trimethylphloroglucinol, another antispasmodic agent. Together, these compounds alleviate discomfort by relaxing the muscles, making the medication effective for various spasm-related conditions.
Orglu Tablet 80mg Uses
Orglu Tablet 80 mg is an antispasmodic medication commonly
used to alleviate pain and discomfort caused by muscle spasms in various
conditions. It is particularly effective for treating spasms associated with
irritable bowel syndrome (IBS), diarrhea, dysentery, renal colic, biliary
colic, and menstrual cramps (dysmenorrhea). Additionally, when combined with rest, it can be used as an adjunct treatment for spasms during delayed labor or to manage contractions during pregnancy.
The tablet is indicated for functional pain disorders of the
digestive and biliary tracts, as well as acute painful spasms of the urinary
tract and gynecological conditions. Its therapeutic role includes relieving
acute spasmodic pain and managing contractions related to pregnancy, providing
symptomatic relief and improving patient comfort in these scenarios.
DOSAGE AND ADMINISTRATION
Method of administration:
Oral; it can be taken without regard to meal. The tablets should be swallowed whole with a glass of water.
Dosage
The usual dose is 6 coated tablets per 24 hours; one to two tablets of Orglu" per dose, spaced 6 to 8 hours
Missed dose: If a dose is missed, the patient should not be advised to take a double dose to make up for it.
Side Effects of Orglu
- Constipation: Difficulty passing stools.
- Transient bradycardia: Temporary slowing of the heart, followed by rapid heart rate, palpitations, and arrhythmias.
- Reduced bronchial secretions: Decreased respiratory fluids, causing dryness.
- Urinary urgency and retention: Trouble emptying the bladder or feeling the need to urinate frequently.
- Pupil dilation and loss of accommodation: Enlarged pupils with difficulty focusing on nearby objects.
- Photophobia: Increased sensitivity to light.
- Dry mouth: Reduced salivary flow causing dryness.
- Drug interaction: Should not be taken with potent analgesics like morphine.
SPECIAL POPULATIONS
Pregnancy safety
No significant problems have been identified when using this
medication at the recommended dose during pregnancy, but it should only be used
if necessary.
Uses during pregnancy
Phloroglucinol and
trimethylphloroglucinol may be used under medical supervision for conditions
like irritable bowel syndrome, diarrhea, dysentery, renal colic, biliary colic,
and dysmenorrhea.
Side effects during pregnancy
Possible side effects include constipation, heart rate
fluctuations (bradycardia and tachycardia), urinary urgency, dry mouth,
flushing, and dilated pupils. Regular monitoring by healthcare professionals is
recommended.
Lactation
The available data do not indicate whether this drug passes into breast milk: it is not recommended during breastfeeding.
Precaution
Avoid combining phloroglucinol with major
painkillers like morphine or its derivatives due to their potential to cause
spasms.
Warnings
- Use antimuscarinics cautiously in individuals with Down syndrome, children, and the elderly.
- Exercise caution in cases of gastro-esophageal reflux disease, diarrhea, and ulcerative colitis.
- Be cautious in patients with acute myocardial infarction, hypertension, and conditions involving tachycardia (such as hyperthyroidism, heart failure, and after cardiac surgery).
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